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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
11.82
Human Site:
S168
Identified Species:
20
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
S168
A
V
E
S
I
Q
D
S
P
L
P
K
K
A
E
Chimpanzee
Pan troglodytes
XP_518477
346
39236
S168
A
V
E
S
I
Q
D
S
P
L
P
K
K
A
E
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
S168
A
V
E
S
L
R
D
S
P
L
P
K
K
A
E
Dog
Lupus familis
XP_538923
388
42549
P210
A
E
G
I
L
A
F
P
P
P
L
K
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
P163
V
T
S
A
A
P
S
P
P
V
T
K
E
E
E
Rat
Rattus norvegicus
NP_001101670
340
38058
S162
P
V
T
S
A
A
P
S
P
P
L
T
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
P157
P
V
P
A
A
A
A
P
A
P
A
P
A
P
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
P163
Q
Q
Q
T
A
D
K
P
A
P
G
S
V
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
D153
P
P
N
K
D
I
V
D
A
K
L
S
K
V
P
Honey Bee
Apis mellifera
XP_001120828
342
39209
S164
S
E
G
I
V
N
G
S
A
K
Q
N
H
K
L
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
Q87
T
A
T
S
K
L
E
Q
A
T
K
A
A
D
E
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
D175
Q
A
Q
K
I
G
L
D
V
V
D
A
P
Q
P
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
I146
G
N
S
N
T
N
P
I
P
P
N
P
S
H
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
K163
S
K
L
P
E
I
Q
K
P
D
V
V
L
P
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
100
86.6
20
N.A.
20
33.3
N.A.
6.6
N.A.
N.A.
0
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
40
40
N.A.
13.3
N.A.
N.A.
13.3
N.A.
6.6
20
20
20
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
15
0
15
29
22
8
0
36
0
8
15
15
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
22
15
0
8
8
0
0
8
0
% D
% Glu:
0
15
22
0
8
0
8
0
0
0
0
0
22
22
43
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
15
0
0
8
8
0
0
0
8
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
0
15
22
15
0
8
0
0
0
0
0
0
8
% I
% Lys:
0
8
0
15
8
0
8
8
0
15
8
36
29
8
0
% K
% Leu:
0
0
8
0
15
8
8
0
0
22
22
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
15
0
0
0
0
8
8
0
0
0
% N
% Pro:
22
8
8
8
0
8
15
29
58
36
22
15
8
15
22
% P
% Gln:
15
8
15
0
0
15
8
8
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
15
36
0
0
8
36
0
0
0
15
8
0
0
% S
% Thr:
8
8
15
8
8
0
0
0
0
8
8
8
0
0
8
% T
% Val:
8
36
0
0
8
0
8
0
8
15
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _